Prolonged Use of Benztropine in Movement Disorders Raises Concern: Discrepancy Between Psychiatry and Primary Care Prescriptions

In a recent study, researchers performed a retrospective analysis of healthcare claims to investigate the real-world treatment patterns of benztropine and understand healthcare providers’ treatment methods for drug-induced movement disorders. The results showed that benztropine is frequently used for movement disorders other than tardive dyskinesia (TD)—often for periods exceeding 3 months—with psychiatry professionals more likely than primary care providers to prescribe benztropine as per guidelines. Researchers concluded that prolonged use of benztropine is concerning due to the potential risks of aggravating TD or causing other adverse effects.

Reference: Chepke C, Benning B, Cicero S, et al. Investigating Real-World Benztropine Usage Patterns in Movement Disorders: Claims Analysis and Health Care Provider Survey Results. Prim Care Companion CNS Disord. 2023;25(4):22m03472. doi: 10.4088/PCC.22m03472

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