Evaluating the Susceptibility to Tardive Dyskinesia in Patients With Schizophrenia
In a study involving 216 patients with schizophrenia, researchers investigated the link between polymorphisms in oxidative stress-related genes and adenosine receptor gene with tardive dyskinesia (TD) occurrence and cognitive impairments. Patients were separated into two groups: TD group (n=157) and non-TD group (n=59). The extraction of DNA was completed by using a high-salt method, as well as SNP genotyping. The Abnormal Involuntary Movement Scale, Positive and Negative Syndrome Scale, and Repeated Battery for Assessment of Neuropsychological Status were used to measure TD severity, psychopathology, and cognitive functioning. In this group of patients, it was found that the interaction of oxidative stress-related genes and adenosine receptor gene might contribute to TD susceptibility and severity.
RE-KINECT Study Results: Physical Wellness and Social Functioning Impact
In a real-world study of possible patients with tardive dyskinesia (TD) treated with antipsychotics, researchers aimed to understand its impact on patient health and social functioning
Dr. Stacy Finkbeiner Explores the Effects of Tardive Dyskinesia on Life’s Key Domains in a Groundbreaking Study
In this YouTube video, Stacy Finkbeiner, PhD, discusses a study published in The Journal of Clinical Psychiatry on the profound impact of tardive dyskinesia (TD) on patients’ lives across physical, psychological, social, and professional realms. The survey, conducted in the United States, reveals that TD significantly impacts various aspects of life, including motor function, sleep, emotional well-being, social interaction, and employment. Notably, over one-third of those surveyed have skipped or ceased their medication due to the severity of their TD symptoms.
Study Shows Tardive Dyskinesia Significantly Lowers Quality of Life, Especially Among Patients With Schizophrenia
Researchers of a study investigated how tardive dyskinesia (TD) impacts the quality of life in patients with bipolar disorder, major depressive disorder, and schizophrenia. Using a web-based survey and various assessment tools, the study found that patients with TD experienced significantly lower health-related quality of life (HRQoL) and greater social withdrawal than those without TD. The impact was more pronounced in physical health domains and was most severe in patients with schizophrenia.
The study concluded that while all patients with these mental health conditions had a lower HRQoL compared with the general population, those suffering from TD were even more adversely affected.
Survey Shows Tardive Dyskinesia Severely Impacts Quality of Life Across Multiple Domains
In a study, 269 patients with tardive dyskinesia (TD) were surveyed to evaluate the disorder’s impact on their quality of life. The findings revealed that most patients experienced moderate-to-severe physical challenges due to TD, including difficulties with speaking, eating, and sleeping. Psychologically, patients felt embarrassed and anxious, leading to social withdrawal. Socially, TD impacted patients’ relationships and increased stigma. Professionally, it led to significant work impairment and hindered career progress.
The study emphasizes that TD’s effects are diverse and profound, influencing more than just motor functions and significantly reducing patients’ overall wellbeing and daily life.
Study Shows Tardive Dyskinesia Movements Lead to Negative Perceptions in Employment and Social Interactions
In a study, researchers aimed to better understand how tardive dyskinesia (TD) impacts perceptions in professional and social settings. Using a randomized digital survey, participants watched videos of actors either simulating tardive dyskinesia (TD) or not. The study found that individuals displaying TD movements were viewed less favorably in terms of employment prospects, attractiveness in dating, and potential for friendship. Researchers concluded the significance of the survey in its quantification of the professional and social stigmas linked with TD movements, highlighting potential challenges in employment, relationships, and social support for those affected.
Shedding Light on Tardive Dyskinesia: A Video Discussion With Michael Asbach
In a recent interview, hosted by Matthew Shapiro and Haley Amering, they welcomed Dr. Michael Asbach to discuss tardive dyskinesia (TD) to shed light on this often misunderstood drug-induced movement disorder. Dr. Asbach emphasized that TD is not limited to individuals with severe mental illnesses like schizophrenia; it can also impact people on various medications for different conditions. Shapiro stresses the importance of awareness, urging individuals to discuss any abnormal movements with their healthcare provider. Ultimately, the video aims to raise awareness about TD during TD Awareness Week, highlighting the significance of recognizing symptoms and seeking appropriate medical guidance.
Study Reveals Comorbidities and Outcomes in Psychiatric Inpatients With Tardive Dyskinesia: Implications for Severe Illness and Healthcare Costs
Researchers of a study analyzed comorbidities and outcomes in psychiatric inpatients with tardive dyskinesia (TD). The study used a case-control design with data from the Nationwide Inpatient Sample, involving 77,022 adult inpatient admissions for mood disorders and schizophrenia. TD was found to be more common in older adults (50-64 years) and occurred in similar proportions among men and women. Patients with TD had a higher likelihood of cardio-metabolic comorbidities, including obesity, hypertension, and diabetes, compared with those without TD.
The researchers concluded that psychiatric inpatients with TD tend to have more severe illness, with those having schizophrenia and bipolar disorders being at the highest risk, and the presence of TD is associated with poorer hospital outcomes, including longer stays and higher costs for acute inpatient care.
Pregnant Woman Develops Nystagmus from Metoclopramide Hydrochloride: A Cautionary Tale for Healthcare Providers
Researchers of a report reviewed the case of a 15-week pregnant woman who developed drug-induced nystagmus, involuntary eye movement, after being prescribed metoclopramide hydrochloride, a medication frequently used for gastrointestinal issues such as nausea and vomiting. After several tests, it was determined that the metoclopramide hydrochloride was the probable cause of the nystagmus. Upon discontinuation, her symptoms disappeared.
Study Finds Patients With Tardive Dyskinesia Report Greater Impact on Quality of Life Than Healthcare Providers
A study presented at the International Association of Parkinsonism and Related Disorders World Congress found that patients with tardive dyskinesia (TD) perceive a greater impact on their quality of life compared with healthcare providers. The respondents rated the extent of TD’s impact across psychological/emotional, physical, professional, and social domains using a 10-point Likert scale.
The results showed that patients and providers both reported the psychological/emotional domain as the most impacted by TD. Patients also reported a greater impact on the physical domain compared with providers. In terms of the professional domain, patients reported a significantly higher impact across all eight subdomains, particularly in interactions at work/school and the ability to perform tasks independently. Overall, patients reported a greater impact of TD across all domains vs providers.
